The Anti-Human C5a receptor (CD88), Biotin (clone 8D6) (rat IgG2a) Antibody from MyBioSource.com is a Rat Monoclonal antibody. This antibody recognizes Human antigen. The Anti-Human C5a receptor (CD88), Biotin (clone 8D6) (rat IgG2a) Antibody has been validated for the following applications: Immunohistochemistry.
Description
This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors. Applications for this clone include flow cytometry, immunohistochemisty (frozen sections) and receptor blockage assays (unpublished results)